Description

4-Chloro-Thieno[3,2-D]Pyrimidine-6-Carboxamide is a high-value heterocyclic building block and pharmaceutical intermediate of significant interest in modern organic synthesis. This compound matters for its role as a versatile precursor in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. Pharmaceutical R&D teams and fine chemical manufacturers need this material for constructing complex molecular architectures targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology Probe Development: Used to create tool compounds for studying specific enzyme pathways and target validation.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for clinical candidates.
• Academic Research: Utilized in university and institutional labs for novel heterocyclic chemistry methodology and drug discovery projects.

Basic Information

Product Name	4-Chloro-Thieno[3,2-D]Pyrimidine-6-Carboxamide
CAS No.	1431411-18-5
Molecular Formula	C7H4ClN3OS
Molecular Weight	213.64 g/mol
Synonyms	4-Chlorothieno[3,2-d]pyrimidine-6-carboxamide; 4-Chloro-6-carbamoylthieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidine-6-carboxamide, 4-chloro-; 1431411-18-5; 4-Chloro-thieno[3,2-d]pyrimidine-6-carboxylic acid amide; 4-Cl-Thieno[3,2-d]pyrimidine-6-CA
EINECS	Contact for details

Quality Control

Our 4-Chloro-Thieno[3,2-D]Pyrimidine-6-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with complete analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.