Description

4-Methoxy-3-Methyl-5-(Trifluoromethyl)Aniline is a high-value, multi-functional aromatic amine building block characterized by its methoxy, methyl, and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique substitution pattern imparts desirable electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-transport layers in display technologies.
• Polymer & Resin Modifiers: Incorporated into specialty polymers to modify thermal stability, solubility, and surface properties.
• Dye & Pigment Precursor: Utilized in the synthesis of high-performance, light-fast organic dyes and pigments.
• Cross-coupling Reactions: Acts as a versatile substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions for complex molecule assembly.

Basic Information

Product Name	4-Methoxy-3-Methyl-5-(Trifluoromethyl)Aniline
CAS No.	1431329-84-8
Molecular Formula	C9H10F3NO
Molecular Weight	205.18 g/mol
Synonyms	3-Methyl-4-methoxy-5-(trifluoromethyl)aniline; 5-(Trifluoromethyl)-3-methyl-4-methoxyaniline; 4-Methoxy-3-methyl-5-trifluoromethylaniline; 4-Methoxy-3-methyl-α,α,α-trifluoro-m-toluidine; 2-Amino-6-methoxy-α,α,α-trifluoro-m-xylene; Benzenamine, 4-methoxy-3-methyl-5-(trifluoromethyl)-; 1431329-84-8
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-Methyl-5-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. This compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.