Description

3,5-Difluoro-4-Methylbenzaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides where the difluoromethylbenzene moiety enhances bioavailability and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where fluorine atoms improve electronic properties and thermal stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to alter physical properties such as chemical resistance, thermal stability, and refractive index.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex biaryl systems.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3,5-Difluoro-4-Methylbenzaldehyde
CAS No.	1429902-14-6
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	4-Methyl-3,5-difluorobenzaldehyde; 3,5-Difluoro-p-tolualdehyde; 3,5-Difluoro-4-methylbenzenecarboxaldehyde; 4-Methyl-3,5-difluorobenzenecarboxaldehyde; 1429902-14-6; Benzaldehyde, 3,5-difluoro-4-methyl-
EINECS	Contact for details

Quality Control

Every batch of 3,5-Difluoro-4-Methylbenzaldehyde is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.