Description

For-Met-Leu-Amc CAS NO 1429788-64-6 is a specialized fluorogenic peptide substrate designed for the sensitive detection and quantification of protease enzyme activity. This compound is critical for biochemical research and pharmaceutical development, enabling precise kinetic studies and high-throughput screening assays. It is primarily utilized by researchers and quality control laboratories in the biotechnology, pharmaceutical, and diagnostic industries.

Application

• Protease Activity Assays: A key substrate for fluorometric assays targeting specific proteolytic enzymes.
• High-Throughput Screening (HTS): Enables rapid screening of potential drug candidates that modulate protease activity in pharmaceutical discovery.
• Enzyme Kinetics Studies: Used to determine kinetic parameters (Km, Vmax) for characterizing protease function and inhibition.
• Diagnostic Development: Serves as a core component in developing clinical diagnostic tests for diseases involving dysregulated protease pathways.
• Biochemical Research: Essential tool for studying protease roles in cellular processes like apoptosis, signal transduction, and protein degradation.
• Quality Control in Biologics: Monitors the presence and activity of proteases during the manufacturing of therapeutic proteins and antibodies.

Basic Information

Product Name	For-Met-Leu-Amc
CAS No.	1429788-64-6
Molecular Formula	C24H34N4O6S
Molecular Weight	506.62 g/mol
Synonyms	Formyl-Methionyl-Leucyl-7-Amino-4-Methylcoumarin; Formyl-Met-Leu-AMC; N-Formyl-Met-Leu-AMC; fMLP-AMC; fMet-Leu-AMC; N-Formyl-Methionyl-Leucyl-AMC; Chemotactic Peptide Substrate AMC; Fluorogenic Formyl Peptide
EINECS	Contact for details

Quality Control

Every batch of For-Met-Leu-Amc is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and batch-to-batch consistency suitable for sensitive research applications. A detailed Certificate of Analysis (COA) documenting identity, purity (HPLC), and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.