Description

3-Bromo-5,6,7,8-Tetrahydropyrazolo[5,1-B]Quinazolin-9(4H)-One is a high-value brominated heterocyclic building block with the CAS number 1429309-42-1. This compound is critical for medicinal chemistry research and pharmaceutical development, serving as a versatile scaffold for creating novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing targeted libraries and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study biological pathways and protein function.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients with herbicidal or insecticidal properties.
• Fine Chemical Manufacturing: Integrated into multi-step synthetic routes for producing complex, high-value specialty chemicals.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new heterocyclic chemistry.

Basic Information

Product Name	3-Bromo-5,6,7,8-Tetrahydropyrazolo[5,1-B]Quinazolin-9(4H)-One
CAS No.	1429309-42-1
Molecular Formula	C11H10BrN3O
Molecular Weight	280.12 g/mol
Synonyms	3-Bromo-4,5,6,7-tetrahydro-9H-pyrazolo[5,1-b]quinazolin-9-one; 3-Bromo-5,6,7,8-tetrahydro-4H-pyrazolo[5,1-b]quinazolin-9-one; 1429309-42-1; 3-Bromotetrahydropyrazoloquinazolinone; Pyrazolo[5,1-b]quinazolin-9(4H)-one, 3-bromo-5,6,7,8-tetrahydro-
EINECS	Contact for details

Quality Control

Our 3-Bromo-5,6,7,8-Tetrahydropyrazolo[5,1-B]Quinazolin-9(4H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.