Description

3-Bromo-8-Methoxy-6,7-Dihydro-5H-Cyclopenta[D]Pyrazolo[1,5-A]Pyrimidine CAS NO 1429309-28-3 is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: The pyrazolopyrimidine core is a privileged structure in the design of potent and selective kinase inhibitors for oncology applications.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study biological processes and validate new drug targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	3-Bromo-8-Methoxy-6,7-Dihydro-5H-Cyclopenta[D]Pyrazolo[1,5-A]Pyrimidine
CAS No.	1429309-28-3
Molecular Formula	C₁₁H₁₀BrN₃O
Molecular Weight	280.12 g/mol
Synonyms	3-Bromo-8-methoxy-6,7-dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidine; 6,7-Dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidine, 3-bromo-8-methoxy-; 1429309-28-3; 3-Bromo-8-methoxy-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidine; Cyclopenta[d]pyrazolo[1,5-a]pyrimidine, 3-bromo-8-methoxy-6,7-dihydro-5H-
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-8-Methoxy-6,7-Dihydro-5H-Cyclopenta[D]Pyrazolo[1,5-A]Pyrimidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.