Description

5-(Piperazin-1-Yl)Pyrimidine Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the creation of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and receptor modulators.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Biochemical Tool Compound: Utilized in biochemical assays and as a reference standard for analytical method development and validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	5-(Piperazin-1-Yl)Pyrimidine Hydrochloride
CAS No.	1429056-39-2
Molecular Formula	C8H13N5•HCl
Molecular Weight	215.68 g/mol
Synonyms	5-(Piperazin-1-yl)pyrimidine hydrochloride; 5-(1-Piperazinyl)pyrimidine hydrochloride; 5-Piperazin-1-yl-pyrimidine HCl; Pyrimidine, 5-(1-piperazinyl)-, hydrochloride; 1429056-39-2; 5-(Piperazin-1-yl)pyrimidine HCl salt
EINECS	Contact for details

Quality Control

Our 5-(Piperazin-1-Yl)Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.