Description

6-Hydroxy-5-Iodopyrimidin-4(3H)-One is a halogenated pyrimidinone derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables targeted molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with potential biological activity. The CAS number for this product is 1429056-25-6.

Application

This iodinated pyrimidinone serves as a critical synthetic intermediate in several high-value chemical sectors:

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, antiviral agents, and other potential therapeutic molecules.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Organic Synthesis Reagent: Serves as a precursor for further functionalization via cross-coupling reactions or nucleophilic substitutions.
• Material Science Research: Potential monomer or precursor for creating specialized heterocyclic polymers or ligands for metal complexes.

Basic Information

Item	Details
Product Name	6-Hydroxy-5-Iodopyrimidin-4(3H)-One
CAS No.	1429056-25-6
Molecular Formula	C4H3IN2O2
Molecular Weight	237.98 g/mol
Synonyms	5-Iodo-6-hydroxypyrimidin-4(3H)-one; 4(3H)-Pyrimidinone, 6-hydroxy-5-iodo-; 5-Iodoorotic acid lactam; 6-Hydroxy-5-iodo-4-pyrimidinone; 5-Iodo-4,6-dihydroxypyrimidine (tautomer); 5-Iodouracil-6-ol
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-5-Iodopyrimidin-4(3H)-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profiles are provided and available upon request. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.