Description

2-Amino-7-Methyl-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4(3H)-One is a high-purity heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of novel, complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. This product is essential for research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs, especially those focused on kinase inhibitors and other small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, particularly kinase inhibitors.
• Drug Discovery & Medicinal Chemistry: Used as a core scaffold or building block in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Synthesis Research: Employed in academic and industrial R&D for developing new synthetic methodologies involving fused pyrimidine systems.
• Active Pharmaceutical Ingredient (API) Development: Integral to the synthesis of complex target molecules in preclinical and clinical development pipelines.
• Biochemical Research: Utilized as a tool compound for studying enzyme interactions and biological pathways.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	2-Amino-7-Methyl-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4(3H)-One
CAS No.	1428139-88-1
Molecular Formula	C9H12N4O
Molecular Weight	192.22 g/mol
Synonyms	2-Amino-7-methyl-3,4,6,7,8,9-hexahydro-5H-pyrido[3,4-d]pyrimidin-5-one; 7-Methyl-2-amino-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one; 2-Amino-7-methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-ol; CAS 1428139-88-1; Pyrido[3,4-d]pyrimidin-4(3H)-one, 2-amino-5,6,7,8-tetrahydro-7-methyl-; 7-Methyl-2-amino-3,4,6,7,8,9-hexahydro-5H-pyrido[3,4-d]pyrimidin-5-one
EINECS	Contact for details

Quality Control

Our 2-Amino-7-Methyl-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4(3H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding pharmaceutical applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch, detailing all relevant specifications. Our quality commitment aligns with ICH guidelines, and we can support development toward cGMP-grade material as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.