Description

Ethyl 6-Amino-2-Cyclobutyl[1,2,4]Triazolo[1,5-A]Pyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrimidine class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for applications in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Used in the research and production of potential anticancer agents due to the biological relevance of the triazolopyrimidine core.
• Antiviral Agent Synthesis: Employed in creating compounds being investigated for their activity against various viral targets.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying enzyme function and cellular processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical R&D pipelines.

Basic Information

Product Name	Ethyl 6-Amino-2-Cyclobutyl[1,2,4]Triazolo[1,5-A]Pyrimidine-5-Carboxylate
CAS No.	1428139-32-5
Molecular Formula	C12H15N5O2
Molecular Weight	261.28 g/mol
Synonyms	6-Amino-2-cyclobutyl[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid ethyl ester; Ethyl 6-amino-2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylate; 2-Cyclobutyl-6-amino-[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid ethyl ester; 1428139-32-5; [1,2,4]Triazolo[1,5-a]pyrimidine-5-carboxylic acid, 6-amino-2-cyclobutyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Amino-2-Cyclobutyl[1,2,4]Triazolo[1,5-A]Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.