Description

(7-Methyl-4-Oxo-3,4,5,6,7,8-Hexahydropyrido[3,4-D]Pyrimidin-2-Yl)Cyanamide is a high-purity, advanced pharmaceutical intermediate belonging to the hexahydropyridopyrimidine class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly for oncology and inflammatory diseases.
• Kinase Inhibitor Synthesis: Serves as a core scaffold for constructing potent and selective kinase inhibitors, a major class of targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency, selectivity, and pharmacokinetic properties of lead compounds.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions in cellular assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	(7-Methyl-4-Oxo-3,4,5,6,7,8-Hexahydropyrido[3,4-D]Pyrimidin-2-Yl)Cyanamide
CAS No.	1428139-20-1
Molecular Formula	C10H11N5O
Molecular Weight	217.23 g/mol
Synonyms	2-Cyanamino-7-methyl-3,4,5,6,7,8-hexahydro-1H-pyrido[3,4-d]pyrimidin-4-one; 7-Methyl-2-(cyanamino)-5,6,7,8-tetrahydro-4H-pyrido[3,4-d]pyrimidin-4-one; (7-Methyl-4-oxo-3,4,5,6,7,8-hexahydro-1H-pyrido[3,4-d]pyrimidin-2-yl)carbamonitrile; Hexahydropyridopyrimidine cyanamide derivative; CAS 1428139-20-1
EINECS	Contact for details

Quality Control

Our (7-Methyl-4-Oxo-3,4,5,6,7,8-Hexahydropyrido[3,4-D]Pyrimidin-2-Yl)Cyanamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.