Description

2-[(Dimethylamino)Methylene]-6-Fluoroindan-1-One is a high-purity fluorinated indanone derivative, serving as a critical advanced pharmaceutical intermediate. Its molecular structure makes it a valuable synthon for constructing complex molecules in medicinal chemistry, particularly for developing active pharmaceutical ingredients (APIs). This compound is essential for research and production in pharmaceutical, agrochemical, and fine chemical synthesis, where precise chemical building blocks are required.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and stability.
• Organic Synthesis: Acts as a versatile precursor for complex organic transformations, including cyclization and condensation reactions in fine chemical manufacturing.
• Material Science Research: Investigated for the development of specialty chemicals and functional materials due to its unique electronic properties.
• Academic & R&D Laboratories: Employed in university and corporate research settings for method development and exploratory chemistry projects.

Basic Information

Product Name	2-[(Dimethylamino)Methylene]-6-Fluoroindan-1-One
CAS No.	1427462-76-7
Molecular Formula	C₁₃H₁₄FNO
Molecular Weight	219.26 g/mol
Synonyms	6-Fluoro-2-[(dimethylamino)methylene]-1-indanone; 2-(Dimethylaminomethylene)-6-fluoro-1-indanone; 6-Fluoro-2-(dimethylaminomethylene)indan-1-one; 2-(Dimethylaminomethylene)-6-fluoroindan-1-one; 6-Fluoro-2-[(dimethylamino)methylene]indan-1-one; 1427462-76-7; 2-(N,N-Dimethylaminomethylene)-6-fluoro-1-indanone
EINECS	Contact for details

Quality Control

Our 2-[(Dimethylamino)Methylene]-6-Fluoroindan-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.