Description

Methyl 2-Amino-6-[4-(Trifluoromethyl)Pyrimidin-2-Yl]-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-3-Ca is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for oncology, neurology, and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially kinase inhibitors.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in research laboratories.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical companies with custom synthesis and scale-up projects.
• Academic Research: Employed in university and institutional labs for investigating novel heterocyclic chemistry and biological activity.
• Process Chemistry: Serves as a starting material or intermediate for developing and optimizing robust, scalable manufacturing routes for APIs.

Basic Information

Product Name	Methyl 2-Amino-6-[4-(Trifluoromethyl)Pyrimidin-2-Yl]-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-3-Ca
CAS No.	1427460-39-6
Molecular Formula	C14H12F3N5OS
Molecular Weight	355.34 g/mol
Synonyms	2-Amino-6-[4-(trifluoromethyl)pyrimidin-2-yl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid methyl ester; Methyl 2-amino-6-(4-(trifluoromethyl)pyrimidin-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate; 1427460-39-6; CAS 1427460-39-6
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-6-[4-(Trifluoromethyl)Pyrimidin-2-Yl]-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-3-Ca is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.