Description

5-Chloro-2-(Chloromethyl)Pyrimidine Hydrochloride is a high-purity, synthetically valuable pyrimidine derivative. This compound serves as a critical pharmaceutical intermediate and versatile chemical building block for constructing complex molecules. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce functionalized pyrimidine scaffolds into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with pyrimidine-based structures.
• Chemical Research & Development: Versatile reagent for medicinal chemistry, process chemistry, and the discovery of new bioactive molecules.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, dyes, and advanced materials requiring chloromethylpyrimidine motifs.
• Nucleoside/Nucleotide Analog Synthesis: Intermediate in the preparation of modified nucleosides for biochemical and therapeutic applications.

Basic Information

Product Name	5-Chloro-2-(Chloromethyl)Pyrimidine Hydrochloride
CAS No.	1427454-12-3
Molecular Formula	C5H5Cl2N2•HCl
Molecular Weight	199.47 g/mol (Free base: 162.01 g/mol)
Synonyms	2-(Chloromethyl)-5-chloropyrimidine hydrochloride; 5-Chloro-2-(chloromethyl)pyrimidine HCl; 5-Chloro-2-chloromethylpyrimidine hydrochloride; 2-Chloromethyl-5-chloropyrimidine hydrochloride; Pyrimidine, 5-chloro-2-(chloromethyl)-, hydrochloride; 5-Chloro-2-(chloromethyl)pyrimidine monohydrochloride
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Chloromethyl)Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for use as a pharmaceutical intermediate. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.