Description

4-Bromo-3-Fluoro-2-Hydroxybenzaldehyde is a versatile halogenated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its molecular structure, featuring bromine, fluorine, and a phenolic hydroxyl group ortho to the aldehyde, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the halogen atoms contribute to bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chelating ligands in coordination chemistry and catalysis, leveraging the ortho-hydroxyaldehyde motif.
• Material Science Research: Employed in the synthesis of functional organic molecules for organic light-emitting diodes (OLEDs), liquid crystals, and advanced polymers.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags, affinity labels, and other molecular probes for studying biological systems.

Basic Information

Product Name	4-Bromo-3-Fluoro-2-Hydroxybenzaldehyde
CAS No.	1427373-29-2
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	2-Hydroxy-4-bromo-3-fluorobenzaldehyde; 4-Bromo-3-fluoro-2-hydroxybenzaldehyde; 3-Fluoro-4-bromo-2-hydroxybenzaldehyde; 2-Formyl-5-bromo-6-fluorophenol; 5-Bromo-6-fluoro-2-hydroxybenzaldehyde; 6-Fluoro-5-bromo-2-hydroxybenzaldehyde; 4-Bromo-3-fluoro-2-hydroxy-benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluoro-2-Hydroxybenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.