Description

C-[4-(1-Fluoro-1-Methyl-Ethyl)-Pyrimidin-5-Yl]-Methylamine is a high-value pyrimidine derivative building block designed for advanced organic synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where its unique fluorinated alkyl-substituted pyrimidine core enables the creation of novel bioactive molecules. It is primarily utilized by medicinal chemists and process development scientists for constructing complex molecular architectures, including potential active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Serves as a crucial building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Chemical Biology Probe Development: Used to create labeled or modified molecules for studying biological pathways and target engagement.
• Material Science Research: Potential precursor for specialty polymers or organic electronic materials due to its heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	C-[4-(1-Fluoro-1-Methyl-Ethyl)-Pyrimidin-5-Yl]-Methylamine
CAS No.	1427195-33-2
Molecular Formula	C8H12FN3
Molecular Weight	169.20 g/mol
Synonyms	5-(Aminomethyl)-4-(1-fluoro-1-methylethyl)pyrimidine; 4-(1-Fluoro-1-methylethyl)-5-pyrimidinemethanamine; (4-(1-Fluoro-1-methylethyl)pyrimidin-5-yl)methanamine; 5-(Aminomethyl)-4-(2-fluoropropan-2-yl)pyrimidine; C-[4-(1-Fluoro-1-Methyl-Ethyl)-Pyrimidin-5-Yl]-Methylamine; CAS 1427195-33-2
EINECS	Contact for details

Quality Control

Our C-[4-(1-Fluoro-1-Methyl-Ethyl)-Pyrimidin-5-Yl]-Methylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical quality attributes. We support development and commercial projects with material produced under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.