Description

4-(1,1-Difluoroethyl)Pyrimidine-5-Carbonitrile is a high-value, fluorinated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique structural motif, which combines a difluoroethyl group with a pyrimidine-carbonitrile core, enabling precise modulation of molecular properties in target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the development of specialty chemicals and functional materials, such as liquid crystals or organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-(1,1-Difluoroethyl)Pyrimidine-5-Carbonitrile
CAS No.	1427195-16-1
Molecular Formula	C7H5F2N3
Molecular Weight	169.13 g/mol
Synonyms	4-(1,1-Difluoroethyl)-5-pyrimidinecarbonitrile; 5-Cyano-4-(1,1-difluoroethyl)pyrimidine; Pyrimidine-5-carbonitrile, 4-(1,1-difluoroethyl)-; 1427195-16-1; 4-(Difluoroethyl)pyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-(1,1-Difluoroethyl)Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids/bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.