Description

C-(4-Trifluoromethyl-Pyrimidin-5-Yl)-Methylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its pyrimidine core and trifluoromethyl functional group. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the biological activity of the pyrimidine scaffold.
• Chemical Research & Development: Serves as a versatile precursor for creating novel chemical libraries in medicinal chemistry and material science.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and molecular recognition studies.
• Fluorinated Compound Production: Acts as a source of the trifluoromethyl group for introducing fluorine atoms into target molecules to enhance metabolic stability and lipophilicity.

Basic Information

Product Name	C-(4-Trifluoromethyl-Pyrimidin-5-Yl)-Methylamine Hydrochloride
CAS No.	1427195-09-2
Molecular Formula	C7H7ClF3N3
Molecular Weight	225.60 g/mol
Synonyms	5-(Aminomethyl)-4-(trifluoromethyl)pyrimidine hydrochloride; (4-Trifluoromethylpyrimidin-5-yl)methanamine hydrochloride; 5-(Aminomethyl)-4-(trifluoromethyl)pyrimidine HCl; 4-(Trifluoromethyl)-5-pyrimidinemethanamine hydrochloride; 5-(Trifluoromethyl)pyrimidine-4-methanamine hydrochloride; 4-Trifluoromethyl-5-aminomethylpyrimidine hydrochloride; 5-(Aminomethyl)-4-trifluoromethylpyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our C-(4-Trifluoromethyl-Pyrimidin-5-Yl)-Methylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.