Description

Compstatin Analog Peptide Cp40 is a potent and selective cyclic peptide inhibitor of the complement system component C3. This compound is a critical research tool and therapeutic candidate for modulating the complement cascade, a key driver of inflammatory and autoimmune diseases. It is essential for researchers and developers in pharmaceutical R&D, immunology, and biotechnology focused on novel treatments for conditions like age-related macular degeneration (AMD), paroxysmal nocturnal hemoglobinuria (PNH), and other complement-mediated disorders.

Application

• Biomedical Research: Fundamental studies on the role of the complement system in disease pathology and immune regulation.
• Drug Discovery & Development: Serving as a lead compound or reference standard in the development of novel complement-targeted therapeutics.
• In Vitro Diagnostics: Used in assay development to screen for complement inhibitors or to study complement activation pathways.
• Preclinical Studies: Evaluation of efficacy and pharmacokinetics in animal models of complement-driven diseases.
• Biochemical Reagent: A high-purity tool for studying protein-protein interactions involving C3 and its convertases.

Basic Information

Product Name	Compstatin Analog Peptide Cp40
CAS No.	1427001-89-5
Molecular Formula	C78H122N24O22
Molecular Weight	1723.96 g/mol
Synonyms	Compstatin Cp40; Cp40 Peptide; Complement C3 Inhibitor Cp40; Ac-Ile-[Cys-Val-Trp(Me)-Gln-Asp-Trp-Sar-Ala-His-Arg-Cys]-mIle-NH2 (cyclic 4-13 disulfide); 4(MeW)/R-Gln-Asp-Trp-Sar-Ala-His-Arg-Cys]-mIle-NH2; Cyclic Peptide Cp40; POT-4 Analog
EINECS	Contact for details

Quality Control

Every batch of Compstatin Analog Peptide Cp40 is manufactured and analyzed under strict quality protocols to ensure the highest standards of purity and biological activity. Our quality assurance includes comprehensive analytical testing by HPLC, MS, and amino acid analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and content is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.