Description

4-Chloro-3-Isobutyl-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is a critical building block in the synthesis of targeted therapeutic agents, offering significant value in research and development for its specific molecular architecture. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel small-molecule drugs, particularly kinase inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent kinase inhibitors and other targeted therapeutics.
• Biochemical Research: Used as a reference standard or a core scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• API Development: Serves as a crucial building block in the development and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic pathways and biological activities of pyrazolopyrimidine derivatives.

Basic Information

Product Name	4-Chloro-3-Isobutyl-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	1424941-66-1
Molecular Formula	C10H13ClN4
Molecular Weight	224.69 g/mol
Synonyms	4-Chloro-3-isobutyl-1-methyl-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 4-chloro-3-(2-methylpropyl)-1-methyl-; 4-Chloro-3-(2-methylpropyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidine; 4-Chloro-1-methyl-3-(2-methylpropyl)-1H-pyrazolo[3,4-d]pyrimidine; Pyrazolopyrimidine derivative CAS 1424941-66-1
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Isobutyl-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.