Description

n-[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thiourea is a high-purity, functionalized pyrimidine derivative designed for advanced chemical synthesis and research. This compound serves as a critical building block in the development of novel active ingredients, offering a unique trifluoromethylated phenylpyrimidine scaffold. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for lead optimization and the creation of new molecular entities with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine-thiourea structure.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for specialty polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	n-[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thiourea
CAS No.	1424940-60-2
Molecular Formula	C12H9F3N4S
Molecular Weight	298.29 g/mol
Synonyms	1-[4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl]thiourea; N-(4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)thiourea; 2-Thioureido-4-phenyl-6-(trifluoromethyl)pyrimidine; Thiourea, N-[4-phenyl-6-(trifluoromethyl)-2-pyrimidinyl]-; 1424940-60-2
EINECS	Contact for details

Quality Control

Our n-[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thiourea is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.