Description

2-(Difluoromethyl)Aniline Hydrochloride is a high-purity, specialty organic intermediate of significant importance in advanced chemical synthesis. Its value lies in the unique reactivity of the difluoromethyl-aniline moiety, which serves as a critical building block for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated aromatic amines.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluoromethyl group enhances biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalytic systems and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: An essential compound for academic and industrial research focused on introducing fluorine atoms into complex molecules.
• Fine Chemical Production: Used in multi-step synthetic routes for producing other high-value, fluorinated fine chemicals and dyes.

Basic Information

Product Name	2-(Difluoromethyl)Aniline Hydrochloride
CAS No.	1422344-12-4
Molecular Formula	C7H8ClF2N
Molecular Weight	179.59 g/mol
Synonyms	2-(Difluoromethyl)benzenamine hydrochloride; 1-Amino-2-(difluoromethyl)benzene hydrochloride; o-(Difluoromethyl)aniline hydrochloride; Benzenamine, 2-(difluoromethyl)-, hydrochloride; 2-(Difluoromethyl)phenylamine hydrochloride; 2-Amino-alpha,α-difluorotoluene hydrochloride; 2-(Difluoromethyl)aniline HCl
EINECS	Contact for details

Quality Control

Every batch of 2-(Difluoromethyl)Aniline Hydrochloride is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure compliance with exacting purity standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.