Description

n-(1,7-Dioxa-10-Azaspiro[4.6]Undecan-3-Ylmethyl)-5-Fluoropyrimidin-2-Amine is a sophisticated heterocyclic organic compound featuring a unique spirocyclic and pyrimidine structure. This molecule is of significant interest in advanced pharmaceutical research and development, particularly as a key intermediate or building block for novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of targeted therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used as a specialized building block for constructing complex molecular libraries in drug discovery programs.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and diagnostic assays due to its reactive amine group.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the fused spirocyclic and fluoropyrimidine motifs into target molecules.
• Agrochemical Research: May be investigated as an intermediate for developing new crop protection agents with specific biological activity.

Basic Information

Product Name	n-(1,7-Dioxa-10-Azaspiro[4.6]Undecan-3-Ylmethyl)-5-Fluoropyrimidin-2-Amine
CAS No.	1422066-59-8
Molecular Formula	C13H17FN4O2
Molecular Weight	280.30 g/mol
Synonyms	5-Fluoro-N-[(1,7-dioxa-10-azaspiro[4.6]undecan-3-yl)methyl]pyrimidin-2-amine; 2-Pyrimidinamine, 5-fluoro-N-[(1,7-dioxa-10-azaspiro[4.6]undecan-3-yl)methyl]-; 1422066-59-8; 5-Fluoro-N-((1,7-dioxa-10-azaspiro[4.6]undecan-3-yl)methyl)pyrimidin-2-amine; Spirocyclic fluoropyrimidine amine; 5-Fluoro-2-((1,7-dioxa-10-azaspiro[4.6]undecan-3-yl)methylamino)pyrimidine
EINECS	Contact for details

Quality Control

Our n-(1,7-Dioxa-10-Azaspiro[4.6]Undecan-3-Ylmethyl)-5-Fluoropyrimidin-2-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.