Description

Benzenamine, 5-Bromo-4-Fluoro-2-(Trifluoromethyl)- is a high-value, multi-halogenated aniline derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromo, fluoro, and trifluoromethyl substituents, makes it an essential intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, where the halogenated aniline core contributes to enhanced biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of molecular probes, affinity tags, and bioconjugation reagents.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex, halogenated dyes and pigments with specific color fastness and spectral properties.

Basic Information

Product Name	Benzenamine, 5-Bromo-4-Fluoro-2-(Trifluoromethyl)-
CAS No.	1421599-52-1
Molecular Formula	C7H4BrF4N
Molecular Weight	258.01 g/mol
Synonyms	5-Bromo-4-fluoro-2-(trifluoromethyl)aniline; 2-Amino-5-bromo-4-fluoro-alpha,alpha,α-trifluorotoluene; 5-Bromo-4-fluoro-2-(trifluoromethyl)benzenamine; 2-(Trifluoromethyl)-5-bromo-4-fluoroaniline; 5-Bromo-4-fluoro-alpha,alpha,α-trifluoro-o-toluidine; 1-Amino-5-bromo-4-fluoro-2-(trifluoromethyl)benzene; 5-Bromo-4-fluoro-2-trifluoromethylphenylamine
EINECS	Contact for details

Quality Control

Our production of Benzenamine, 5-Bromo-4-Fluoro-2-(Trifluoromethyl)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure consistent high purity and reliable performance in your synthetic workflows. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.