Description

2-Amino-7,8-Dihydro-6H-Pyrido[3,2-D]Pyrimidine-5-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex heterocyclic molecules, offering significant value in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) disease research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Employed in the synthesis of kinase inhibitors and other targeted cancer therapies due to its pyrido[3,2-d]pyrimidine core.
• CNS-Active Compound Synthesis: A key component in creating molecules designed to cross the blood-brain barrier for treating neurological disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical R&D pipelines.
• Academic Research: Utilized in university and institutional labs for studying novel heterocyclic chemistry and biological activity.

Basic Information

Product Name	2-Amino-7,8-Dihydro-6H-Pyrido[3,2-D]Pyrimidine-5-Carboxylic Acid tert-Butyl Ester
CAS No.	1421312-14-2
Molecular Formula	C12H16N4O2
Molecular Weight	248.28 g/mol
Synonyms	tert-Butyl 2-amino-7,8-dihydro-6H-pyrido[3,2-d]pyrimidine-5-carboxylate; 2-Amino-5-(tert-butoxycarbonyl)-7,8-dihydro-6H-pyrido[3,2-d]pyrimidine; 2-Amino-6H-pyrido[3,2-d]pyrimidine-5-carboxylic acid, 7,8-dihydro-, 1,1-dimethylethyl ester; 1421312-14-2; Pyrido[3,2-d]pyrimidine-5-carboxylic acid derivative; BOC-protected pyridopyrimidine intermediate
EINECS	Contact for details

Quality Control

Our 2-Amino-7,8-Dihydro-6H-Pyrido[3,2-D]Pyrimidine-5-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.