Description

2-Phenyl-7,8-Dihydro-6H-Pyrido[3,2-D]Pyrimidine-5-Carboxylic Acid tert-Butyl Ester is a high-value pharmaceutical intermediate and building block in organic synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and other therapeutic areas. It is primarily needed by R&D laboratories, contract research organizations (CROs), and pharmaceutical manufacturers engaged in the synthesis of novel drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex drug molecules, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Biology Probes: Serves as a scaffold for creating tool compounds to study biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for novel heterocyclic chemistry and methodology development.

Basic Information

Product Name	2-Phenyl-7,8-Dihydro-6H-Pyrido[3,2-D]Pyrimidine-5-Carboxylic Acid tert-Butyl Ester
CAS No.	1421312-01-7
Molecular Formula	C21H23N3O2
Molecular Weight	349.43 g/mol
Synonyms	tert-Butyl 2-phenyl-7,8-dihydro-6H-pyrido[3,2-d]pyrimidine-5-carboxylate; 2-Phenyl-6,7,8,9-tetrahydro-5H-pyrido[3,2-d]pyrimidine-5-carboxylic acid tert-butyl ester; 1421312-01-7; Pyrido[3,2-d]pyrimidine-5-carboxylic acid, 7,8-dihydro-2-phenyl-, 1,1-dimethylethyl ester; 2-Phenyl-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidine-5-tert-butyl carboxylate
EINECS	Contact for details

Quality Control

Our 2-Phenyl-7,8-Dihydro-6H-Pyrido[3,2-D]Pyrimidine-5-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for advanced research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.