Description

2-Methyl-2-Propanyl 2-(Methylsulfonyl)-7,8-Dihydropyrido[3,2-D]Pyrimidine-5(6H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for oncology and anti-inflammatory drug candidates.
• Kinase Inhibitor Research: Serves as a core scaffold for the design and development of novel kinase inhibitors due to its dihydropyridopyrimidine moiety.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of proprietary compounds for clients.
• Biochemical Tool Compound: May be utilized in biochemical assays to study specific enzyme interactions and pathways in academic and industrial research settings.

Basic Information

Product Name	2-Methyl-2-Propanyl 2-(Methylsulfonyl)-7,8-Dihydropyrido[3,2-D]Pyrimidine-5(6H)-Carboxylate
CAS No.	1421311-97-8
Molecular Formula	C14H19N3O4S
Molecular Weight	325.38 g/mol
Synonyms	tert-Butyl 2-(methylsulfonyl)-7,8-dihydro-5H-pyrido[3,2-d]pyrimidine-5-carboxylate; 2-Methyl-2-propanyl 2-(methylsulfonyl)-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidine-5-carboxylate; 2-(Methylsulfonyl)-7,8-dihydro-5H-pyrido[3,2-d]pyrimidine-5-carboxylic acid tert-butyl ester; 1421311-97-8; tert-Butyl 2-(methanesulfonyl)-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-Propanyl 2-(Methylsulfonyl)-7,8-Dihydropyrido[3,2-D]Pyrimidine-5(6H)-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.