Description

(tert-Butoxy)Carbonyl D-β-Homoglutamic Acid(Obzl) is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound is a critical building block for researchers and manufacturers developing novel pharmaceutical peptides and bioactive molecules. It is primarily used by the pharmaceutical, biotechnology, and life sciences industries for applications requiring precise stereochemistry and side-chain protection.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the research and development of new peptide-based drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected D-β-homoglutamic acid residue.
• Bioconjugation: Serves as a linker or spacer molecule in the design of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology: Employed in the synthesis of modified peptides for studying enzyme function and protein-protein interactions.
• Proteomics Research: Useful for creating isotopically labeled or otherwise tagged peptides for mass spectrometry analysis.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing complex, non-standard amino acid derivatives.

Basic Information

Product Name	(tert-Butoxy)Carbonyl D-β-Homoglutamic Acid(Obzl)
CAS No.	1421258-63-0
Molecular Formula	C17H23NO6
Molecular Weight	337.37 g/mol
Synonyms	Boc-D-β-Homo-Glu(OBzl)-OH; Boc-D-β-homoglutamic acid 1-benzyl ester; (2R)-2-{[(tert-Butoxy)carbonyl]amino}pentanedioic acid 5-benzyl ester; D-β-Homoglutamic acid, N-Boc, γ-benzyl ester; N-Boc-D-β-homoglutamic acid γ-benzyl ester; Boc-D-β-hGlu(OBzl)-OH; D-Boc-β-homoglutamic acid benzyl ester
EINECS	Contact for details

Quality Control

Our (tert-Butoxy)Carbonyl D-β-Homoglutamic Acid(Obzl) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.