Description

2-Chloro-6-(5-Isopropyl-2-Methylphenyl)-4-((1R,3R,5S)-3-Methoxy-8-Azabicyclo[3.2.1]Octan-8-Yl)-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine is a sophisticated, high-purity pharmaceutical intermediate and research chemical. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring advanced molecular scaffolds. It is primarily needed by pharmaceutical R&D laboratories, process development chemists, and manufacturers specializing in the production of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes for the commercial production of target APIs.
• Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control in API manufacturing.
• Biochemical Tool Compound: Utilized in pharmacological assays to study specific biological pathways and receptor interactions.
• Custom Synthesis: A starting point for the contract manufacturing of specialized, non-commercial chemical entities for advanced research.

Basic Information

Product Name	2-Chloro-6-(5-Isopropyl-2-Methylphenyl)-4-((1R,3R,5S)-3-Methoxy-8-Azabicyclo[3.2.1]Octan-8-Yl)-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine
CAS No.	1421253-42-0
Molecular Formula	C25H31ClN4O
Molecular Weight	438.99 g/mol
Synonyms	8-Azabicyclo[3.2.1]octane, 2-chloro-6-(5-isopropyl-2-methylphenyl)-4-(3-methoxy-8-azabicyclo[3.2.1]oct-8-yl)-5,6,7,8-tetrahydro-4-pyrido[4,3-d]pyrimidine; (1R,3R,5S)-8-[2-Chloro-6-(5-isopropyl-2-methylphenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]-3-methoxy-8-azabicyclo[3.2.1]octane; UNII-8K8V5QWG2C; 1421253-42-0; 2-Chloro-6-(5-isopropyl-2-methylphenyl)-4-((1R,3R,5S)-3-methoxy-8-azabicyclo[3.2.1]octan-8-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(5-Isopropyl-2-Methylphenyl)-4-((1R,3R,5S)-3-Methoxy-8-Azabicyclo[3.2.1]Octan-8-Yl)-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and rigorous control of residual solvents and impurities to meet pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm
Assay	97.0% - 102.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.