Description

(S)-(5-Fluoro-2,3-Dihydrobenzo[B][1,4]Dioxin-2-Yl)Methanol is a high-purity chiral building block and synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its value lies in its defined stereochemistry and the presence of a fluorinated benzodioxane scaffold, which is a privileged structure in medicinal chemistry for modulating drug-like properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of fluorination and stereochemistry on biological activity and metabolic stability.
• Agrochemical Synthesis: Serves as a building block for developing novel, high-performance pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Potential precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Can be utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Item	Details
Product Name	(S)-(5-Fluoro-2,3-Dihydrobenzo[B][1,4]Dioxin-2-Yl)Methanol
CAS No.	1420537-26-3
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	(S)-5-Fluoro-2,3-dihydro-1,4-benzodioxin-2-methanol; (2S)-5-Fluoro-2,3-dihydro-1,4-benzodioxine-2-methanol; (S)-(-)-5-Fluoro-2,3-dihydro-1,4-benzodioxin-2-ylmethanol; (S)-5-Fluoro-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxine; (S)-enantiomer of 5-Fluoro-2,3-dihydrobenzo[b][1,4]dioxin-2-ylmethanol; (S)-Fluorobenzodioxanyl methanol; Chiral Fluorinated Benzodioxane Methanol
EINECS	Contact for details

Quality Control

Our (S)-(5-Fluoro-2,3-Dihydrobenzo[B][1,4]Dioxin-2-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to ensure high enantiomeric excess (ee) and identity confirmation by NMR and mass spectrometry. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency, purity, and traceability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.