Description

2-Bromo-[5-[(1-Methyl-4-Piperidinyl)Methoxy]-2-Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a distinct brominated pyrimidine core. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates, especially within oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Kinase Inhibitor Development: Serves as a precursor in the creation of potent and selective kinase inhibitors, a major class of oncology drugs.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and drug design methodologies.

Basic Information

Product Name	2-Bromo-[5-[(1-Methyl-4-Piperidinyl)Methoxy]-2-Pyrimidine
CAS No.	1419101-22-6
Molecular Formula	C11H16BrN3O
Molecular Weight	286.17 g/mol
Synonyms	2-Bromo-5-[(1-methyl-4-piperidinyl)methoxy]pyrimidine; 5-[(1-Methyl-4-piperidinyl)methoxy]-2-bromopyrimidine; 2-Bromo-5-((1-methylpiperidin-4-yl)methoxy)pyrimidine; 1419101-22-6; UNII-9K3H2J8Q7F; 9K3H2J8Q7F; SCHEMBL21806227; DTXSID60664669
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-[5-[(1-Methyl-4-Piperidinyl)Methoxy]-2-Pyrimidine is produced under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.