Description

7-Bromo-5-Methyl-5H-Pyrrolo-[3,2-D]Pyrimidine-6-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant value for its role as a critical building block in the synthesis of novel, small-molecule drug candidates, particularly in oncology and targeted therapies. It is primarily sought after by research institutions, contract research and manufacturing organizations (CROs/CMOs), and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for novel drug discovery programs.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation & Probe Development: The aldehyde functional group allows for site-specific conjugation, useful in creating chemical probes for biochemical assays.
• Academic Research: Employed in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	7-Bromo-5-Methyl-5H-Pyrrolo-[3,2-D]Pyrimidine-6-Carbaldehyde
CAS No.	1419101-10-2
Molecular Formula	C8H6BrN3O
Molecular Weight	240.06 g/mol
Synonyms	7-Bromo-5-methyl-5H-pyrrolo[3,2-d]pyrimidine-6-carboxaldehyde; 5H-Pyrrolo[3,2-d]pyrimidine-6-carboxaldehyde, 7-bromo-5-methyl-; 1419101-10-2; 7-Bromo-5-methyl-pyrrolo[3,2-d]pyrimidine-6-carbaldehyde; 7-Bromo-5-methyl-5H-pyrrolo[3,2-d]pyrimidine-6-carbaldehyde
EINECS	Contact for details

Quality Control

Our 7-Bromo-5-Methyl-5H-Pyrrolo-[3,2-D]Pyrimidine-6-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.