Description

1-Azetidinecarboxylic Acid, 3-[(3,4-Dihydro-4-Oxopyrido[2,3-D]Pyrimidin-2-Yl)Amino]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel kinase inhibitors and other targeted therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of innovative active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, especially those targeting specific enzymatic pathways.
• Kinase Inhibitor Research: Used in the development and optimization of novel kinase inhibitors for oncology and other therapeutic areas.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore new chemical entities and improve drug potency and selectivity.
• API Development: Integral in the process development and scale-up stages for new active pharmaceutical ingredients.
• Biochemical Research: Utilized as a tool compound in biochemical assays to study enzyme function and inhibition mechanisms.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Item	Detail
Product Name	1-Azetidinecarboxylic Acid, 3-[(3,4-Dihydro-4-Oxopyrido[2,3-D]Pyrimidin-2-Yl)Amino]-, 1,1-Dimethylethyl Ester
CAS No.	1418747-15-5
Molecular Formula	C17H21N5O3
Molecular Weight	343.38 g/mol
Synonyms	tert-Butyl 3-((3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl)amino)azetidine-1-carboxylate; 1-Boc-3-((3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl)amino)azetidine; 1,1-Dimethylethyl 3-[(3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-1-azetidinecarboxylate; Azetidine-1-carboxylic acid, 3-[(3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-, 1,1-dimethylethyl ester; Boc-3-APPA; 1418747-15-5
EINECS	Contact for details

Quality Control

Our 1-Azetidinecarboxylic Acid, 3-[(3,4-Dihydro-4-Oxopyrido[2,3-D]Pyrimidin-2-Yl)Amino]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.