Description

Ethyl-[2-(Pyrrolidin-3-Ylmethoxy)-Pyrimidin-4-Yl]-Amine Hydrochloride is a high-purity, non-nucleoside reverse transcriptase inhibitor (NNRTI) intermediate of significant pharmaceutical importance. This compound is valued for its role in the synthesis of novel antiviral agents, particularly in HIV research and development pipelines. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers serving the life sciences sector.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of next-generation non-nucleoside reverse transcriptase inhibitors (NNRTIs) for antiviral therapies.
• Antiviral Drug Research: Serves as a critical scaffold in medicinal chemistry programs targeting HIV-1 and other retroviral infections.
• Biochemical Research: Used in enzymatic studies and as a reference standard for investigating reverse transcriptase inhibition mechanisms.
• Preclinical Development: Employed in the production of active pharmaceutical ingredients (APIs) for toxicology and pharmacokinetic studies.
• Custom Synthesis: A starting material for the preparation of structurally related analogs for structure-activity relationship (SAR) exploration.

Basic Information

Product Name	Ethyl-[2-(Pyrrolidin-3-Ylmethoxy)-Pyrimidin-4-Yl]-Amine Hydrochloride
CAS No.	1417793-83-9
Molecular Formula	C11H19ClN4O
Molecular Weight	258.75 g/mol
Synonyms	4-(Ethylamino)-2-[(3-pyrrolidinyl)methoxy]pyrimidine Hydrochloride; 2-[(Pyrrolidin-3-yl)methoxy]-4-(ethylamino)pyrimidine Hydrochloride; 4-(Ethylamino)-2-(pyrrolidin-3-ylmethoxy)pyrimidine HCl; Ethyl-[2-(pyrrolidin-3-ylmethoxy)pyrimidin-4-yl]amine hydrochloride; NNRTI Intermediate 1417793-83-9
EINECS	Contact for details

Quality Control

Our Ethyl-[2-(Pyrrolidin-3-Ylmethoxy)-Pyrimidin-4-Yl]-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and related substances. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.