Description

3-(4-Ethylamino-Pyrimidin-2-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, where precise molecular structure and consistent quality are non-negotiable.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Development: Key structural component in the research and production of kinase inhibitors for oncology and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Custom Synthesis: Serves as a starting material or intermediate for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.
• Biochemical Research: Employed in biochemical assays and as a tool compound for probing biological mechanisms.

Basic Information

Product Name	3-(4-Ethylamino-Pyrimidin-2-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1417793-74-8
Molecular Formula	C16H26N4O3
Molecular Weight	322.41 g/mol
Synonyms	1-Boc-3-[(4-ethylamino)pyrimidin-2-yloxy]piperidine; tert-Butyl 3-[(4-(ethylamino)pyrimidin-2-yl)oxy]piperidine-1-carboxylate; 3-[(4-(Ethylamino)-2-pyrimidinyl]oxy]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 3-[[4-(ethylamino)-2-pyrimidinyl]oxy]-1-piperidinecarboxylate; 3-(4-Ethylamino-pyrimidin-2-yloxy)-piperidine-1-carboxylic acid tert-butyl ester; BOC-3-(4-Ethylamino-pyrimidin-2-yloxy)-piperidine
EINECS	Contact for details

Quality Control

Our production of 3-(4-Ethylamino-Pyrimidin-2-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with cGMP standards where applicable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or with appropriate desiccant to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.