Description

4-(6-Cyclopropylamino-Pyrimidin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate critical for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering precise structural control for medicinal chemists. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and antiviral research pipelines.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Serves as a core structural component in the research and synthesis of potential kinase inhibitor therapeutics.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for chemical biology studies and the development of new synthetic methodologies.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for potential commercial drug manufacturing.

Basic Information

Product Name	4-(6-Cyclopropylamino-Pyrimidin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1417793-41-9
Molecular Formula	C17H26N4O3
Molecular Weight	334.42 g/mol
Synonyms	tert-Butyl 4-((6-(cyclopropylamino)pyrimidin-4-yl)oxy)piperidine-1-carboxylate; 1-Boc-4-((6-(cyclopropylamino)pyrimidin-4-yl)oxy)piperidine; 4-(6-Cyclopropylamino-pyrimidin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-((6-(cyclopropylamino)pyrimidin-4-yl)oxy)piperidine; BOC-protected 4-(6-cyclopropylaminopyrimidin-4-yloxy)piperidine; CAS 1417793-41-9
EINECS	Contact for details

Quality Control

Every batch of 4-(6-Cyclopropylamino-Pyrimidin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.