Description

Ethyl-[2-((S)-Pyrrolidin-3-Yloxy)-Pyrimidin-4-Yl]-Amine Hydrochloride is a high-purity, chiral organic salt of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block (intermediate) for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for research organizations, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the discovery and scale-up of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates.
• Active Pharmaceutical Ingredient (API) Development: Used in research for constructing the core scaffold of new molecules with targeted biological activity.
• Medicinal Chemistry & Drug Discovery: Employed in structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Process Chemistry & Scale-Up: Serves as a defined starting material for developing robust, scalable manufacturing routes under GMP conditions.
• Biochemical Research: May be utilized as a tool compound or ligand in biochemical assays and target validation studies.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	Ethyl-[2-((S)-Pyrrolidin-3-Yloxy)-Pyrimidin-4-Yl]-Amine Hydrochloride
CAS No.	1417789-16-2
Molecular Formula	C11H19ClN4O
Molecular Weight	258.75 g/mol
Synonyms	4-Pyrimidinamine, 2-[(3S)-3-pyrrolidinyloxy]-N-ethyl-, hydrochloride (1:1); (S)-N-Ethyl-2-(pyrrolidin-3-yloxy)pyrimidin-4-amine hydrochloride; Ethyl-(2-((S)-pyrrolidin-3-yloxy)pyrimidin-4-yl)amine HCl; 1417789-16-2; UNII-8C9S2J8Q2B; 8C9S2J8Q2B
EINECS	Contact for details

Quality Control

Our Ethyl-[2-((S)-Pyrrolidin-3-Yloxy)-Pyrimidin-4-Yl]-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, NMR, and mass spectrometry for structural confirmation. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, ensuring compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.