Description

(2S)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-2-(4-Hydroxycyclohexyl)Acetic Acid is a sophisticated Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its core value lies in enabling the precise, sequential construction of complex peptides and peptidomimetics with high stereochemical fidelity. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the automated, sequential assembly of custom peptide sequences.
• Pharmaceutical Research & Development: Used in the discovery and development of peptide-based drugs targeting metabolic disorders, oncology, and infectious diseases.
• Bioconjugation: Serves as a linker or functional handle for attaching peptides to other molecules, surfaces, or nanoparticles.
• Combinatorial Chemistry Libraries: A valuable component for generating diverse libraries of peptide-like compounds for high-throughput screening.
• Biochemical Probe Development: Incorporated into probes for studying enzyme activity, protein-protein interactions, and cellular signaling pathways.
• Academic Research: Fundamental tool in university and institutional labs for studying peptide structure, function, and synthesis methodologies.

Basic Information

Product Name	(2S)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-2-(4-Hydroxycyclohexyl)Acetic Acid
CAS No.	1416444-92-2
Molecular Formula	C24H27NO6
Molecular Weight	425.47 g/mol
Synonyms	Fmoc-(S)-2-amino-2-(4-hydroxycyclohexyl)acetic acid; Fmoc-4-Hydroxycyclohexylglycine-OH; Fmoc-Hcyg-OH; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(4-hydroxycyclohexyl)acetic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-hydroxycyclohexylglycine; Fmoc-Cyc(4-OH)-OH; Fmoc-protected 4-hydroxycyclohexylglycine; Nα-Fmoc-4-hydroxy-L-cyclohexylglycine
EINECS	Contact for details

Quality Control

Our (2S)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-2-(4-Hydroxycyclohexyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Allow the sealed container to reach ambient temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥99.0% (S-isomer)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.