Description

5,6-Dichloro-2-(3-Pyridinyl)-4-Pyrimidinepropanoic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.
• Process Chemistry Development: Serves as a standard for scaling up and optimizing synthetic routes for API manufacturing.
• Biochemical Tool Compound: Potential use in biochemical assays to study specific enzyme pathways and mechanisms of action.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial chemical entities for client-specific research programs.

Basic Information

Product Name	5,6-Dichloro-2-(3-Pyridinyl)-4-Pyrimidinepropanoic Acid Ethyl Ester
CAS No.	1416372-17-2
Molecular Formula	C14H13Cl2N3O2
Molecular Weight	326.18 g/mol
Synonyms	Ethyl 5,6-dichloro-2-(pyridin-3-yl)-4-pyrimidinepropanoate; 3-[5,6-Dichloro-2-(3-pyridinyl)-4-pyrimidinyl]propanoic Acid Ethyl Ester; 5,6-Dichloro-2-(3-pyridyl)-4-pyrimidinepropionic Acid Ethyl Ester; 1416372-17-2; Ethyl 3-(5,6-dichloro-2-(pyridin-3-yl)pyrimidin-4-yl)propanoate
EINECS	Contact for details

Quality Control

Our 5,6-Dichloro-2-(3-Pyridinyl)-4-Pyrimidinepropanoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.