Description

5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is a high-purity, heterocyclic building block of significant importance in modern pharmaceutical and agrochemical research. Its core value lies in its functionalized pyrrolopyrimidine scaffold, which serves as a versatile intermediate for the synthesis of targeted small molecule inhibitors. This compound is essential for researchers and manufacturers in the life sciences sector, particularly those developing kinase inhibitors and other therapeutic agents where precise molecular modification is critical.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted cancer therapeutics.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology: Serves as a valuable probe or building block in the study of biological pathways and protein function.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex molecular architectures for material science and drug discovery.
• Bioconjugation: The iodine moiety allows for further functionalization, making it useful in creating labelled compounds or conjugates.

Basic Information

Product Name	5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine
CAS No.	1416354-36-3
Molecular Formula	C6H6IN5
Molecular Weight	275.05 g/mol
Synonyms	5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 2-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidine; 5-Iodo-2-amino-7H-pyrrolo[2,3-d]pyrimidine; 1416354-36-3; 5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-2-ylamine; 7H-Pyrrolo[2,3-d]pyrimidin-2-amine, 5-iodo-
EINECS	Contact for details

Quality Control

Our 5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material traceability and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.