Description

(1S)-1-[2-(Trifluoromethoxy)Phenyl]Ethylamine is a high-purity chiral amine building block of significant importance in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries that require enantiomerically pure intermediates for asymmetric synthesis.

Application

• Key chiral intermediate in the synthesis of novel pharmaceutical candidates, especially central nervous system (CNS) active compounds.
• Building block for the research and development of agrochemicals, including herbicides and fungicides.
• Precursor in the preparation of advanced materials and liquid crystals.
• Versatile starting material for academic and industrial research in asymmetric catalysis and medicinal chemistry.
• Used in the synthesis of ligands for metal-catalyzed cross-coupling reactions.

Basic Information

Item	Details
Product Name	(1S)-1-[2-(Trifluoromethoxy)Phenyl]Ethylamine
CAS No.	1415380-63-0
Molecular Formula	C9H10F3NO
Molecular Weight	205.18 g/mol
Synonyms	(S)-1-[2-(Trifluoromethoxy)phenyl]ethanamine; (S)-1-(2-(Trifluoromethoxy)phenyl)ethylamine; (1S)-1-[2-(Trifluoromethoxy)phenyl]ethan-1-amine; (S)-α-Methyl-2-(trifluoromethoxy)benzylamine; (S)-1-(2-Trifluoromethoxyphenyl)ethylamine; (S)-TFMPEA; (S)-2-(Trifluoromethoxy)phenethylamine enantiomer
EINECS	Contact for details

Quality Control

Our (1S)-1-[2-(Trifluoromethoxy)Phenyl]Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard identification tests, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.