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2-Bromo-6-Chloro-4-(Trifluoromethyl)Benzaldehyde CAS NO 1415130-43-6


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CAS No.:1415130-43-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Bromo-6-Chloro-4-(Trifluoromethyl)Benzaldehyde is a high-purity, multi-functional aromatic aldehyde building block of significant importance in advanced organic synthesis. Its core value lies in its unique halogenated and trifluoromethylated structure, which is critical for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require sophisticated intermediates for the development of novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
  • Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
  • Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its ability to influence molecular polarity and packing.
  • Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for selective palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
  • Fluorine Chemistry Research: An important compound for studying the effects of fluorine substitution on aromatic systems in medicinal and materials chemistry research programs.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name 2-Bromo-6-Chloro-4-(Trifluoromethyl)Benzaldehyde
CAS No. 1415130-43-6
Molecular Formula C8H3BrClF3O
Molecular Weight 287.46 g/mol
Synonyms 2-Bromo-6-chloro-α,α,α-trifluoro-p-tolualdehyde; 4-Bromo-2-chloro-α,α,α-trifluorobenzaldehyde; 6-Chloro-2-bromo-4-(trifluoromethyl)benzaldehyde; Benzaldehyde, 2-bromo-6-chloro-4-(trifluoromethyl)-; 2-Bromo-6-chloro-4-trifluoromethylbenzaldehyde; 1415130-43-6; BCF-TFMBA (abbreviation)
EINECS Contact for details

Quality Control

Every batch of 2-Bromo-6-Chloro-4-(Trifluoromethyl)Benzaldehyde is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon to maintain optimal purity and stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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