Description

3-Fluoro-Benzene-1,2-Diamine Dihydrochloride is a high-purity fluorinated aromatic diamine salt, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a reactive, protected diamine precursor with a fluorine substituent, enabling precise molecular modifications for performance materials. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated benzimidazole and quinoxaline derivatives, which are core structures in various active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides where the fluorine atom enhances bioactivity and environmental stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polyimides, polybenzimidazoles, and other high-performance polymers with enhanced thermal and chemical resistance.
• Dye & Pigment Manufacturing: Acts as a starting material for synthesizing complex fluorinated azo dyes and organic pigments, improving color fastness and spectral properties.
• Ligand & Catalyst Development: Utilized to create novel chelating ligands for metal-organic frameworks (MOFs) and homogeneous catalysis, leveraging the electronic effects of the fluorine atom.
• Research & Development: A valuable reagent for medicinal chemistry and chemical biology research, enabling structure-activity relationship (SAR) studies and the exploration of new chemical entities.

Basic Information

Product Name	3-Fluoro-Benzene-1,2-Diamine Dihydrochloride
CAS No.	1414959-15-1
Molecular Formula	C6H8Cl2FN2
Molecular Weight	207.05 g/mol
Synonyms	1,2-Diamino-3-fluorobenzene Dihydrochloride; 3-Fluoro-1,2-phenylenediamine Dihydrochloride; 3-Fluoro-o-phenylenediamine Dihydrochloride; 3-Fluorobenzene-1,2-diamine Dihydrochloride; 3-Fluoro-1,2-benzenediamine Dihydrochloride; 3-F-DAB Dihydrochloride; 3-Fluorocatechol Dihydrochloride (amine form)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-Benzene-1,2-Diamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.