Description

2,4-Bis(Trifluoromethyl)-6-Bromophenol is a high-value, multi-functional halogenated phenolic intermediate. This compound is prized for its unique combination of a phenolic hydroxyl group, a bromine substituent, and two trifluoromethyl groups, which impart significant lipophilicity, stability, and electronic effects. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and advanced materials sectors for constructing complex molecular architectures. Its structural features make it a critical building block for active pharmaceutical ingredients (APIs) and specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a core or side-chain unit in the production of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving charge transport and thermal properties.
• Polymer Modification: Incorporated as a monomer or additive to create specialty fluoropolymers with enhanced chemical resistance, low surface energy, and improved durability.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to develop novel ligands for catalysis, leveraging the electron-withdrawing nature of the substituents.
• Advanced Material Research: Employed in academic and industrial R&D for creating novel organic frameworks and functional materials with tailored properties.

Basic Information

Product Name	2,4-Bis(Trifluoromethyl)-6-Bromophenol
CAS No.	1414870-83-9
Molecular Formula	C9H3BrF6O
Molecular Weight	321.02 g/mol
Synonyms	6-Bromo-2,4-bis(trifluoromethyl)phenol; 2-Bromo-3,5-bis(trifluoromethyl)phenol; Phenol, 6-bromo-2,4-bis(trifluoromethyl)-; 3-Bromo-2-hydroxy-1,5-bis(trifluoromethyl)benzene; 2,4-Bis(trifluoromethyl)-6-bromophenol; 6-Bromo-α,α,α,α',α',α'-hexafluoro-m-xylen-2-ol; Brominated Hexafluoroxylenol Intermediate
EINECS	Contact for details

Quality Control

Every batch of 2,4-Bis(Trifluoromethyl)-6-Bromophenol is manufactured and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC-MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO 9001 standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.