Description

4-Bromo-6-Chloro-2-Trifluoromethylphenol is a halogenated phenol derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique trifluoromethyl and halogen substitution pattern makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylphenol core.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Chemical Biology & Proteomics: Serves as a reactive handle or linker in the design of chemical probes, enzyme inhibitors, and affinity tags.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.
• Academic & Industrial R&D: Employed in discovery chemistry for structure-activity relationship (SAR) studies and library synthesis in medicinal chemistry programs.

Basic Information

Product Name	4-Bromo-6-Chloro-2-Trifluoromethylphenol
CAS No.	1414870-65-7
Molecular Formula	C7H3BrClF3O
Molecular Weight	290.45 g/mol
Synonyms	2-Trifluoromethyl-4-bromo-6-chlorophenol; 4-Bromo-6-chloro-α,α,α-trifluoro-o-cresol; 4-Bromo-6-chloro-2-(trifluoromethyl)phenol; Phenol, 4-bromo-6-chloro-2-(trifluoromethyl)-; 6-Chloro-4-bromo-2-trifluoromethylphenol; BCTFP
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Chloro-2-Trifluoromethylphenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and reducing agents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.