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3-(3-Fluoro-4-Isopropoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine CAS NO 1408087-64-8


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CAS No.:1408087-64-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(3-Fluoro-4-Isopropoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound serves as a critical building block in the research and development of novel kinase inhibitors and targeted cancer therapies. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology firms, and CDMOs (Contract Development and Manufacturing Organizations) engaged in the synthesis of small molecule drug candidates.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of targeted oncology drugs, particularly kinase inhibitors.
  • Biochemical Research: Used as a reference standard or active scaffold in enzymatic assays and structure-activity relationship (SAR) studies.
  • Drug Discovery & Development: Employed in medicinal chemistry programs for the design and optimization of new therapeutic agents.
  • Preclinical Studies: Serves as a starting material for producing compounds used in in vitro and in vivo pharmacological testing.
  • Custom Synthesis: A valuable substrate for contract research organizations (CROs) performing bespoke chemical synthesis for clients.

Basic Information

Product Name 3-(3-Fluoro-4-Isopropoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No. 1408087-64-8
Molecular Formula C14H14FN5O
Molecular Weight 287.29 g/mol
Synonyms 3-(3-Fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(3-fluoro-4-isopropoxyphenyl)-; 1408087-64-8; 3-(3-Fluoro-4-(propan-2-yloxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 3-(3-Fluoro-4-(1-methylethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 3-(3-Fluoro-4-isopropoxyphenyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidine; 4-Amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine
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Quality Control

Our 3-(3-Fluoro-4-Isopropoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (MS) Conforms
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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