Description

Methyl 5-Aminopyrimidine-2-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant building block essential for modern drug discovery and development. This compound serves as a critical intermediate in the synthesis of complex molecules, particularly in the creation of kinase inhibitors and other targeted therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of novel herbicides and fungicides containing pyrimidine motifs.
• Chemical Biology: Employed as a scaffold or precursor for designing molecular probes and enzyme inhibitors.
• Material Science: Potential precursor for the synthesis of functionalized heterocyclic compounds used in advanced materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	Methyl 5-Aminopyrimidine-2-Carboxylate Hydrochloride
CAS No.	1408076-25-4
Molecular Formula	C6H8N3O2·HCl
Molecular Weight	189.61 g/mol
Synonyms	5-Amino-2-pyrimidinecarboxylic acid methyl ester hydrochloride; Methyl 5-aminopyrimidine-2-carboxylate HCl; 2-Pyrimidinecarboxylic acid, 5-amino-, methyl ester, hydrochloride; Methyl 5-amino-2-pyrimidinecarboxylate hydrochloride; 5-Aminopyrimidine-2-carboxylic acid methyl ester hydrochloride salt
EINECS	Contact for details

Quality Control

Our Methyl 5-Aminopyrimidine-2-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and other relevant analytical techniques. Our quality commitment aligns with the standards expected for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.