Description

7-((2-(Trimethylsilyl)Ethoxy)Methyl)-2,4-Dichloro-5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value, multi-functionalized pyrrolopyrimidine derivative designed for advanced synthetic chemistry. This compound serves as a critical versatile synthetic intermediate, enabling the construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D and agrochemical discovery teams for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting the pyrrolopyrimidine scaffold.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic core.
• Chemical Biology Probe Synthesis: The reactive halogen and protected functional groups make it suitable for creating labeled compounds and molecular probes for target identification.
• Material Science Precursor: Serves as a starting material for synthesizing organic electronic materials and ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring complex halogenated heterocycles.

Basic Information

Product Name	7-((2-(Trimethylsilyl)Ethoxy)Methyl)-2,4-Dichloro-5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	1404364-72-2
Molecular Formula	C12H16Cl2IN3OSi
Molecular Weight	444.15 g/mol
Synonyms	2,4-Dichloro-5-iodo-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine; 7-((2-(Trimethylsilyl)ethoxy)methyl)-2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 2,4-dichloro-5-iodo-7-[[2-(trimethylsilyl)ethoxy]methyl]-; SEM-Protected 2,4-Dichloro-5-Iodopyrrolo[2,3-d]pyrimidine; 2,4-Dichloro-5-iodo-7-SEM-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 7-((2-(Trimethylsilyl)Ethoxy)Methyl)-2,4-Dichloro-5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency for research and development. Identity and purity are verified by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is sensitive to strong alkali and should be kept away from such materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.