Description

2-Bromo-5-(2-Chlorophenyl) Pyrimidine is a high-value halogenated pyrimidine derivative, a crucial building block in modern synthetic chemistry. Its molecular architecture, featuring both bromine and chlorine substituents on an aromatic pyrimidine core, makes it an essential intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used as a precursor in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated heterocyclic structure.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to its reactive bromine moiety.
• Ligand and Catalyst Development: Utilized to construct complex chelating ligands for metal catalysts used in asymmetric synthesis.
• Life Science Research: Acts as a biochemical probe or a tagged molecule in proteomics and diagnostic assay development.

Basic Information

Item	Details
Product Name	2-Bromo-5-(2-Chlorophenyl) Pyrimidine
CAS No.	1403764-69-1
Molecular Formula	C10H6BrClN2
Molecular Weight	269.53 g/mol
Synonyms	2-Bromo-5-(2-chlorophenyl)pyrimidine; 5-(2-Chlorophenyl)-2-bromopyrimidine; 2-Bromo-5-(o-chlorophenyl)pyrimidine; Pyrimidine, 2-bromo-5-(2-chlorophenyl)-; 1403764-69-1; 2-Bromo-5-(2-chlorophenyl)pyrimidine; 2-Brom-5-(2-chlorphenyl)pyrimidin (German)
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-(2-Chlorophenyl) Pyrimidine is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure product integrity and traceability. Our standard quality commitment includes rigorous testing for identity, purity, and impurity profiles using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing batch-specific results are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. This material is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.