Description

Methyl 4-(4-Fluorophenyl)Pyrimidine-2-Carboxylate is a high-purity fluorinated pyrimidine derivative, a critical building block in modern organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. Pharmaceutical R&D and fine chemical synthesis laboratories need it to create novel therapeutic candidates targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and liquid crystals.
• Academic & Contract Research: Essential for medicinal chemistry programs and route scouting in academic and CRO (Contract Research Organization) settings.
• Chemical Biology: Employed as a molecular probe or scaffold for studying biological pathways and protein interactions.

Basic Information

Product Name	Methyl 4-(4-Fluorophenyl)Pyrimidine-2-Carboxylate
CAS No.	1401162-80-8
Molecular Formula	C12H9FN2O2
Molecular Weight	232.21 g/mol
Synonyms	Methyl 4-(4-fluorophenyl)pyrimidine-2-carboxylate; 2-Pyrimidinecarboxylic acid, 4-(4-fluorophenyl)-, methyl ester; 4-(4-Fluorophenyl)-2-pyrimidinecarboxylic acid methyl ester; Methyl 4-(p-fluorophenyl)pyrimidine-2-carboxylate; 1401162-80-8; Methyl 4-(4-fluorophenyl)-2-pyrimidinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-(4-Fluorophenyl)Pyrimidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.